Organic bromide salts
Apexbio Technology LLC Propantheline bromide 50-34-0 200mg
Propantheline bromide (CAS 50-34-0) is a small-molecule antagonist of muscarinic acetylcholine receptors (mAChRs) It inhibits cholinergic neurotransmission within smooth muscle tissues resulting in modulation of muscle contractility In biomedical research propantheline bromide is utilized to investigate physiological mechanisms related to smooth muscle disorders such as gastrointestinal or bladder spasms and hyperhidrosis This compound is broadly applied in studies of the autonomic nervous system and serves as a tool for pharmacological exploration of cholinergic signaling pathways
Medchemexpress LLC Propantheline bromide | 50-34-0 | 97.4% | 1 ML
Propantheline bromide is an orally active mAChR antagonist used for research into smooth muscle dysfunction, excessive sweating, cramps or spasms of the stomach, intestines or bladder, and involuntary urination. It hardly crosses the blood-brain barrier and is for research use only.
- Acts as an mAChR antagonist
- Decreases urinary bladder smooth muscle reactivity to Acetylcholine
- Can be used with cholinesterase inhibitors to suppress peripheral side effects
- Available as a solid, or in solution with solvent
TARGETMOL CHEMICALS INC Propantheline bromide 500MG
Also available in 1 mL, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Propantheline bromide (Pro-Banthine) competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. Propantheline Bromide is the bromide salt form of propantheline, a quaternary ammonium compound structurally related to belladonna alkaloids. An aspartic acid residue present in the N-terminal portion of the third transmembrane helix of the muscarinic receptor is believed to form an ionic bond with the tertiary or quaternary nitrogen of the antagonist. Antagonism leads to a reduction of exocrine glands secretions and to relax the bronchial muscle and reduce tone and motility of intestinal smooth muscle. Purity 95%
Sigma Aldrich Fine Chemicals Biosciences Acetylcholine bromide >=99% | 66-23-9 | MFCD00011814 | 100G
Acetylcholine bromide >=99% | Purity: >=99% | Mol Wt: 226.11 | 66-23-9 | MFCD00011814 | 100G
eMolecules Trimethylphenylammonium bromide | 16056-11-4 | MFCD00011788 | 25g
Chem-Impex | Trimethylphenylammonium bromide | 25g | 603112712 | 36833 | | 16056-11-4 | MFCD00011788 | 216.122 | C9H14BrN
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Apexbio Technology LLC Propantheline bromide 50-34-0 100mg
Propantheline bromide (CAS 50-34-0) is a small-molecule antagonist of muscarinic acetylcholine receptors (mAChRs) It inhibits cholinergic neurotransmission within smooth muscle tissues resulting in modulation of muscle contractility In biomedical research propantheline bromide is utilized to investigate physiological mechanisms related to smooth muscle disorders such as gastrointestinal or bladder spasms and hyperhidrosis This compound is broadly applied in studies of the autonomic nervous system and serves as a tool for pharmacological exploration of cholinergic signaling pathways
